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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAA2 All Species: 16.97
Human Site: S511 Identified Species: 31.11
UniProt: P54646 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54646 NP_006243.2 552 62320 S511 S T T A E S H S L S G S L T G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086410 550 62775 S507 D A E A Q G K S S E V S L T S
Dog Lupus familis XP_546691 722 81319 S681 S V T A E G H S L S G S L T G
Cat Felis silvestris
Mouse Mus musculus Q8BRK8 552 61988 S511 S S T A E N H S L S G S L T G
Rat Rattus norvegicus Q09137 552 62239 S511 S S T A E N H S L S G S L T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506315 519 59478 S476 D A E A P G K S S G A S L T S
Chicken Gallus gallus Q9IA88 798 88848 F726 S Q L L Q P H F F G V S V S P
Frog Xenopus laevis NP_001088426 560 64038 S517 P E F Q A K S S D G S G P S S
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 G849 Q L T A Q L L G E S V M G S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623371 515 58559 K474 K S Y L L D F K S L S N E E E
Nematode Worm Caenorhab. elegans Q95ZQ4 626 70425 M575 T S S M P Q A M S M E A S I E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 K494 V K S P N V V K F E I Q L Y K
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 V582 I E T N N Y L V D F K F D G W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 76.4 73.8 N.A. 97.6 98.1 N.A. 71.1 27.3 75.3 22.3 N.A. N.A. 66.1 53.6 N.A.
Protein Similarity: 100 N.A. 86.7 75.2 N.A. 98.5 99 N.A. 81.1 42.6 85 32.6 N.A. N.A. 77.7 65.6 N.A.
P-Site Identity: 100 N.A. 33.3 86.6 N.A. 86.6 86.6 N.A. 33.3 20 6.6 20 N.A. N.A. 0 0 N.A.
P-Site Similarity: 100 N.A. 40 86.6 N.A. 100 100 N.A. 33.3 40 13.3 33.3 N.A. N.A. 13.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 44.9 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. 62.3 50.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 54 8 0 8 0 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 8 0 0 16 0 0 0 8 0 0 % D
% Glu: 0 16 16 0 31 0 0 0 8 16 8 0 8 8 16 % E
% Phe: 0 0 8 0 0 0 8 8 16 8 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 24 0 8 0 24 31 8 8 8 31 % G
% His: 0 0 0 0 0 0 39 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % I
% Lys: 8 8 0 0 0 8 16 16 0 0 8 0 0 0 8 % K
% Leu: 0 8 8 16 8 8 16 0 31 8 0 0 54 0 0 % L
% Met: 0 0 0 8 0 0 0 8 0 8 0 8 0 0 0 % M
% Asn: 0 0 0 8 16 16 0 0 0 0 0 8 0 0 0 % N
% Pro: 8 0 0 8 16 8 0 0 0 0 0 0 8 0 8 % P
% Gln: 8 8 0 8 24 8 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 39 31 16 0 0 8 8 54 31 39 16 54 8 24 24 % S
% Thr: 8 8 47 0 0 0 0 0 0 0 0 0 0 47 0 % T
% Val: 8 8 0 0 0 8 8 8 0 0 24 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 8 0 0 8 0 0 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _